Knight and Wright have been diagnosed with severe gastroparesis, or stomach paralysis, which their doctors think may have resulted from or been exacerbated by the medication they were taking, Ozempic. If the stomach slows down too much, however, that can cause problems. One of the roles of GLP-1 is to slow the passage of food through the stomach, which helps people feel fuller longer. These and other drugs in this family, which includes medications like tirzepatide and liraglutide, work by mimicking a hormone that’s naturally made by the body, GLP-1. The diabetes drug Ozempic, and its sister drug for weight loss, Wegovy, utilize the same medication, semaglutide. “I’ve almost been off Ozempic for a year, but I’m still not back to my normal,” Wright said. But Wright said she now vomits so frequently that she had to take a leave of absence from her job. Over a year, she said, she lost 80 pounds, which she’s been able to keep off. A low-angle view of a young woman who is weighing herself in a weighing scale Karl Tapales/Moment RF/Getty ImagesĮxperimental drugs aim to surpass weight-loss stars like Ozempic and WegovyĮmily Wright, 38, a teacher in Toronto, started taking Ozempic in 2018.
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